Lets Talk About NAD+
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every cell of the body, crucial for generating energy (ATP), repairing DNA, and regulating metabolism. As a key component of cellular health, NAD+ levels naturally decline with age, leading to increased fatigue and reduced metabolic function.
NAD+ Uses and benefits
Remarkably, ageing is accompanied by a gradual decline in tissue and cellular NAD+ levels in multiple model organisms, including rodents and humans. This decline in NAD+ levels is linked causally to numerous ageing-associated diseases, including cognitive decline, cancer, metabolic disease, sarcopenia and frailty. Many of these ageing-associated diseases can be slowed down and even reversed by restoring NAD+ levels. Therefore, targeting NAD+ metabolism has emerged as a potential therapeutic approach to ameliorate ageing-related disease, and extend the human healthspan and lifespan. This extends into areas of athletic performance and recovery. It shows promise in reducing inflammation. With the use of NAD+ we have see an increase in energy as well.
With most wellness regimens we always recommend a balance of diet, hydration, and physical activity. What we put in our body always affects the out flow of our bodily functions and overall wellness. This wouldn’t be a fix alone but a part of the tools available to live a healthy, potentially long life.
NAD Side effects and Risks
It is generally considered safe, with most side effects being mild, temporary, and dose-dependent. Common side effects include nausea, fatigue, headaches, flushing, and discomfort at the injection site. Potential risks, particularly with high doses or long-term use, include metabolic issues like reduced insulin sensitivity, liver discomfort, and theoretical concerns about tumor growth.
FDA
However, much remains to be learnt about how NAD+ influences human health and ageing biology. Currently, this is an alternative wellness treatment. The FDA has not researched NAD+ properties which currently leaves this therapy as non-approved.